Clinically relevant drug interactions of current antifungal agents

Clinically relevant drug interactions with antiepileptic drugs.

Some patients with difficult-to-treat epilepsy benefit from combination therapy with two or more antiepileptic drugs (AEDs). Additionally, virtually all epilepsy patients will receive, at some time in their lives, other medications for the management of associated conditions. In these situations, clinically important drug interactions may occur. Carbamazepine, phenytoin, phenobarbital and primi...

incidence rate and pattern of clinically relevant potential drug-drug interactions in a large outpatient population of a developing country

the objective of this study was to determine incidence rate, type, and pattern of clinically relevant potential drug-drug interactions (pddis) in a large outpatient population of a developing country. a retrospective, descriptive cross-sectional study was conducted on outpatients’ prescriptions in khorasan razavi province, iran, over 12 months. a list of 25 clinically relevant ddis, which are l...

DGIdb 2.0: mining clinically relevant drug-gene interactions

The Drug-Gene Interaction Database (DGIdb, www.dgidb.org) is a web resource that consolidates disparate data sources describing drug-gene interactions and gene druggability. It provides an intuitive graphical user interface and a documented application programming interface (API) for querying these data. DGIdb was assembled through an extensive manual curation effort, reflecting the combined in...

Clinically important drug interactions.

Valerian: No Evidence for Clinically Relevant Interactions

In recent popular publications as well as in widely used information websites directed to cancer patients, valerian is claimed to have a potential of adverse interactions with anticancer drugs. This questions its use as a safe replacement for, for example, benzodiazepines. A review on the interaction potential of preparations from valerian root (Valeriana officinalis L. root) was therefore cond...